Samaritan's
Alzheimer's Drug Caprospinol Suggests Brain May
be Able to Heal From Alzheimer's Disease
Tuesday
July 10, 2007, 9:35 am ET
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Samaritan Pharmaceuticals Inc. (OTC BB:SPHC.OB), a developer
of innovative drugs, is pleased to announce it has
confirmed Caprospinol's
(SP-233) efficacy in its ability to dramatically
decrease beta amyloid plaque in the brain, accompanied
by a complete recovery of memory back to baseline
(p=0.002), as shown in a Morris water maze task.
This study confirms previously reported in-vitro
data and suggests Caprospinol
may not only slow down Alzheimer's but may also
reverse plaque-related brain injuries associated
with the mind-robbing disease of Alzheimer's.
The
hallmark of Alzheimer's disease is plaque formation
in areas of the brain that control memory and thinking
skills. Plaque can cause swelling and bumps on nerve
cells, making it hard or even impossible for the
cells to communicate. While the cause of Alzheimer's
disease still remains unknown, a growing number
of researchers are indicating that plaque formation
and accumulation may play a role.
The
study was conducted by Samaritan's collaborating
researchers, including Dr. Laurent Lecanu and Dr.
Vassilios Papadopoulos.
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Animal Study Confirms Caprospinol's (SP-233)
Ability to Clear Brain Plaque and Empower
Rat Brain Cells to Recover Memory Function
In
Vivo 'Proof of Concept' Study Proposes Direct
Correlation Between
Removing Beta Amyloid Plaque and Memory Recovery
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Abstract:
http://www.samaritanpharma.com/caprospinol_abstract.pdf
Dr.
Janet Greeson, CEO of Samaritan Pharmaceuticals stated,
``Memory recovery in rats is a lot simpler than curing
Alzheimer's disease in people but these study results
are extremely encouraging. The rats tested with our proprietary
Alzheimer's rat model took on features similar to
the crippling dementia seen in a human's Alzheimer's brain,
and then, by treating the rats with Caprospinol,
the rat's brain cells bounced back with complete memory.''
Samaritan
Pharmaceuticals:
“Transforming Today’s Science Into
Tomorrow’s Cures…”
Samaritan Pharmaceuticals, Inc. is an entrepreneurial
biopharmaceutical company, focused on commercializing
innovative therapeutic products to relieve the suffering
of patients with Alzheimer's disease, Cancer, Cardiovascular
disease, HIV, and Hepatitis-C. Samaritan, in collaboration
with Pharmaplaz, Ireland, is advancing SP-01A, an “oral”
HIV viral-entry inhibitor, to late stage clinical trials
in Europe since it has completed Phase IIb clinical studies
with positive results in the US. Samaritan has three drug
candidates in nonclinical studies to develop IND applications,
it’s building upon the IND application for Caprospinol,
SP-233, to treat Alzheimer's disease patients; evaluating
the use of SP-1000 for acute coronary disease patients;
and the use of SP-10T1 as an "oral treatment"
for Hepatitis-C patients. In addition, Samaritan has acquired
the marketing and sales rights to sell ten revenue-generating
products in Greece and/or various Eastern European countries.
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Disclaimer
The company disclaims any information that is created
by an outside party and endorses only information that
is communicated by its press releases, filings and Website.
This news release contains forward-looking statements
that reflect management's current beliefs about the potential
for its drug candidates, science and technology. However,
as with any biopharmaceutical under development, there
are significant risks and uncertainties in the process
of development and regulatory review. There are no guarantees
that products will prove to be commercially successful.
For additional information about the factors that affect
the company's business, please read the company's latest
Form 10-K filed April 13, 2007. The company undertakes
no duty to update forward-looking statements.
Contact:
The Investor Relations Group
Investor Relations:
Adam Holdsworth
Erica Ruderman
Rachel Colgate
212-825-3210
Samaritan
Pharmaceuticals, Inc.
Kristi Eads
702-735-7001
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