Untitled Document
| PEER-REVIEWED
PUBLICATIONS AND PATENTS |
Peer-Reviewed
Publications | Patents |
 Publications
refer to scientific papers written about a drug by its creators and published
in scientific journals. These publications, called peer-reviewed journals,
are scholarly periodicals requiring each article submitted be judged by
an independent panel of experts (scientific peers) to authenticate the accuracy
of the material. The number of articles printed and the variety of publications
accepting the article serve to underscore the legitimacy of information.
Funding agencies use these articles to determine whether or not to fund,
and if selected, the amount to fund the research or offer an award. |
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HIV
Publications and Abstracts
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Alzheimer's
Disease Publications and Abstracts |
| Publication
and Abstracts |
Product |
Link |
| Neuroscience
148 (2007) 441-453 |
SP-233 |
22R-HYDROXYCHOLESTEROL
INDUCES DIFFERENTIATION OF HUMAN NT2 PRECURSOR (Ntera2/D1 TERATOCARCINOMA)
CELLS |
| Caprospinol Poster
Board Abstract |
SP-233 |
Caprospinol
Improves Brain Histopathology and Recovers Memory Function In A Rat
Model of Alzheimer's Disease |
| Steroids,
2006, 725-735 |
SP-233 |
Results
indicate that Aß1-42 and SP233 exert direct effects on mitochondrial
function and SP-233 protects neuronal cells against Aß-induced
toxicity by targeting Aß directly. |
| Chemistry &
Biodiversity, Vol. 2 (2005) 1571 |
SP-233 |
Methodology
for Multi-Site Ligand - Protein Docking Identification Developed for
the Optimization of Spirostenol Inhibition of ß-Amyloid-Induced
Neurotoxicity |
| Steroids,
2004 69(1):1-16 |
SP-233 |
Identification
of naturally occurring spirostenols preventing beta-amyloid-induced
neurotoxicity |
| Poster Board
Abstract |
SP-233 |
Naturally
occuring 22R-Hydroxycholesterol Derivatives Project Neuronal Cells
Against ß-Amyloid (1-42) Toxicity |
| Poster
Board Abstract |
SP-233 |
The
spirostenol (22S,25S)-(20S)-spirost-5-en-3ß-yl hexanoate prevents
Aß-induced impairment of mitochondrial function and blacks mitochondrial
AB uptake into neuronal cells |
| J Neurochem,
2002, 83, 1110-1119 |
SP-233 |
22R-Hydroxycholesterol
Protects Neuronal Cells from B-Amyloid-Induced Cytotoxicity by Binding
to ß-Amyloid Peptide |
| Poster
Board Abstract |
SP-04 |
In
vitro and in vivo characterization of a novel acetylcholinesterase
inhibitor, dimethyl-carbamic 2, 3-bis-dimethylcarbamoyloxy-6-[4-(4-thyl-piperazin-1-yl)-butyryl]-phenyl
ester |
| Bioorganic &
Medicinal Chemistry Letters 16 (2006) 62777-6280 |
SP-04 |
Three-dimensional
quantitative structure-activity relationship (3D QSAR) of acetylcholinesterase
(AChE) inhibitors, based on molecular docking scores and comparative
molecular field analysis (CoMFA) |
| Neuropharmacology,
49 (2005): 86-96 |
SP-08 |
Identification,
design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone
derivatives with neuroprotective properties against ß-amyloid-induced
toxicity |
| Pharmacology,
2005;74:65-78 |
SP-08 |
Local
Anesthetic Procaine Protects Rat Pheochromocytoma PC12 Cells against
ß-Amyloid-Induced Neurotoxicity |
| Poster
Board Abstract |
SP-sc7 |
A
steroid naturally occuring in the soft water fungi Achlya heterosexualis
induces neurogenesis in vitro and in vivo in rat brain |
| Analytical Biochem,
2004 324(1):123-30 |
AD
Diagnostic |
A
Capillary Gas Chromatography/Mass Spectrometric Method for The Quantification
of Hydroxysteroids in Human Plasma |
| Neurobiology
of Aging, 24 (2003) 57-65 |
AD
Diagnostic |
Oxidative
stress-mediated DHEA formation in Alzheimer's disease pathology |
| Pharmacology,
2006;76:19–33 |
AD
Rat Model |
Beta-Amyloid
and Oxidative Stress Jointly Induce Neuronal Death, Amyloid Deposits,
Gliosis, and Memory Impairment in the Rat Brain |
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Cancer
Publications and Abstracts |
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Cardiovascular
Disease Publications and
Abstracts |
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