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BREAST
CANCER PREDICTIVE DIAGNOSTIC
Samaritan has series of preclinical studies to develop
a simple blood test which can detect down to one cancer
cell in two miillion cells for early detection of
fast growing cancer cells.
Our
diagnostic blood test would potentially measure whether
a breast cancer tumor is aggressive in nature as well
as the likelihood of a cancerous tumor to metastasize
and spread cancer throughout the body. The test offers
a faster prognosis of a breast cancer biopsy (1- 7
days compared to the traditional 3-weeks).
To
date, an invasive biopsy is the only way to determine
if a potential trouble spot is cancerous or benign.
A non invasive blood test could be the first, preferred,
diagnostic tool; to predict whether a breast tumor
is cancerous, possibly being able to detect one single
aggressive cancer cell, out of millions of blood cells.
Also, it could be used as a measuring tool to monitor
the success of chemotherapy, radiation and other drug
treatments for aggressive cancer. Another benefit
of Samaritan's breast cancer diagnostic -- avoiding
the costs and negative effects of unnecessary chemotherapy.
The
science of this predictive medicine diagnostic is
in the detection of high levels of the protein peripheral-type
benzodiazepine receptor (PBR) to determine tumor aggressiveness,
which has been demonstrated with in vitro.
- The
risk of cancer increases with age - about 76% of
all cancers are diagnosed at age 55 and older.
- Since
1990, breast cancer incidence rates have increased
predominantly in women age 50 and older. Source:
"Older Americans, 2005 Survey"
Journals:
J Recept Signal Transduct Res., 2003; 23(2-3):225-38
Molecular Endocrinology 2001; 15:2211-2228
Cancer Research, 1999, 59, 831-842
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